About the CONNECT Trial
General information
This study was set up by the Erasmus MC Sophia Children’s Hospital and is being carried out by doctors and researchers from various hospitals in Europe. This research has been approved by the medical ethics review committee. This is a special committee that assesses whether a study is safe for the participants and whether the rights of these participants are guaranteed.
Goal of the trial
We are investigating which treatment gives the best results for patients with a CPAM who do not have any symptoms after birth. We compare an operation with a wait-and-see policy.
See below to find more detailed information for parents, regarding the trial.
A detailed description of the study can be found in the following document
Previous research by the CONNECT research group:
Our most recent work
- Dossche LWJ, Kersten CM, Zanen-van den Adel T, et al. Long-term neurodevelopment in children with resected congenital lung abnormalities. Eur J Pediatr. 2023;182(9):3845-3855. doi: 10.1007/s00431-023-05054-5
- Kersten CM, Jansen MDG, Zuidweg MJP, Wijnen RMWH, Krasemann TB, Schnater JM. The Diagnostics and Management of Bronchopulmonary Sequestration: An International Survey among Specialized Caregivers. Eur J Pediatr Surg. Published online March 6, 2024. doi: 10.1055/s-0044-1782237
- Kersten CM, Hermelijn SM, Dossche LWJ, et al. COllaborative Neonatal Network for the first European CPAM Trial (CONNECT): a study protocol for a randomised controlled trial. BMJ Open. 2023;13(3):e071989. Published 2023 Mar 17. doi: 10.1136/bmjopen-2023-071989
- Kersten CM, Hermelijn SM, Mullassery D, et al. The Management of Asymptomatic Congenital Pulmonary Airway Malformation: Results of a European Delphi Survey. Children (Basel). 2022;9(8):1153. Published 2022 Jul 30. doi: 10.3390/children9081153
- Hermelijn S, Kersten C, Mullassery D, et al. Development of a core outcome set for congenital pulmonary airway malformations: study protocol of an international Delphi survey. BMJ Open. 2021;11(4):e044544. Published 2021 Apr 12. doi: 10.1136/bmjopen-2020-044544
